A gofundme page has been set up for the family displaced by the fire. For more information and to donate, click here.
UPDATE (1:41 p.m.) - Firefighters were able to knock down the blaze, but not before it destroyed the mobile home, fire officials told KSBY.
CAL FIRE SLO was called to the area at around 11:15 a.m. for reports of of a fully involved structure fire.
When they arrived, Atascadero Fire Department was on the scene hosing down the fire. CAL FIRE responded with water tenders and multiple fire engines to help knock down the blaze, officials told KSBY.
"The home is totally destroyed by the fire," CAL FIRE SLO Public Information Officer Adan Orozco said. "The fire went through every room of the house, and in a lot of areas, the walls were completely burned through."
No one was home when the fire broke out, though Orozco said the family was away from the home for only about 10 minutes.
No injuries were reported, and investigators are working to determine the fire's cause.
Both lanes of Hwy 41 have reopened to traffic.
(11:27 a.m.) Firefighters responded to a fire at a mobile home on Highway 41 east of Atascadero on Tuesday.
It was reported shortly after 11 a.m. near Homestead Road.
CAL FIRE reported that fire crews arrived to find the home fully involved in fire.
All occupants were reported to be out of the structure.
The California Highway Patrol reported that one lane of the highway was closed because of the fire equipment parked at the scene.
This is a developing story and will be updated with new information as it becomes available.