Highway 46 West, just west of Old Creek Road, was temporarily closed to traffic Monday afternoon due to a crash.
It happened just before 4 p.m.
The California Highway Patrol described it as a "major crash," reportedly involving a vehicle that went off the side of the roadway.
As of 5:25 p.m., the roadway was reopened.
On Highway 41 at Bear Ridge Road, west of the Cerro Alto Campground, a head-on crash also affected traffic. The CHP warned that drivers should expect delays and use highways 1 or 101 as detours.
That crash happened at about 4:45 p.m. The roadway was cleared as of 5:45 p.m.
