UPDATE (8:59 a.m.) - Hwy 46 reopened at the scene of the crash late Saturday night.
In a tweet, Caltrans officials said the road was open to traffic by 11:23 p.m.
The westbound lanes of Highway 46 East near River Grove Drive are now open. https://t.co/WeRrSkEC0q— Caltrans District 5 (@CaltransD5) February 13, 2022
UPDATE (9:30 P.M.) - Cal Fire SLO confirmed that at least eight patients were injured and transported to Twin Cities and Sierra Vista Regional Medical Center.
One person was airlifted to the hospital.
The incident occurred just before 8 p.m. on Highway 46 and River Grove Drive involving multiple vehicles.
Crews remain on scene and westbound Highway 46 will remain closed for a couple of hours.
The cause of the crash is under investigation.
(8:27 p.m.) - First reports of a collision involving multiple vehicles at Highway 46 and Whitely Gardens in Paso Robles came in at 7:51 p.m.
According to Cal Fire SLO, crews are on scene responding to the crash, and all traffic is stopped at Westbound Highway 46.
California Highway Patrol reported on its traffic incidents website that there are at least three vehicles involved with multiple injuries resulting from this collision.
This is a developing story.