UPDATE (12:25 p.m.) - The crash is currently being cleared up.
The CHP is about to open up the other lane.
No injuries were reported.
A SIG Alert was issued following a crash on Highway 101 in San Luis Obispo Wednesday.
It happened at about 11:42 a.m. and reportedly involved two vehicles in the northbound lanes south of the Los Osos Valley Road offramp.
No word on the extent of any injuries but an ambulance has been requested at the scene.
One lane was said to be blocked and CHP reported traffic was backing up to Higuera Street.
This is a developing story and will be updated as information becomes available.