The Cardinals, led by senior running back Adrian Soracco, soared past Cabrillo on Saturday night, 51-6, at Lompoc High School.
The Conquistadores' first drive ended with a fumble, and the Cardinals capitalized with a Soracco touchdown.
Later in the half, with the Conquistadores trailing by 13, Zack Ramos connected with Cade Mcnamee down the middle of the field, as the junior barrelled his way across the goal line to put Cabrillo on the board.
Cabrillo is back in action next week against Nipomo, while Bishop Diego clashes with St. Bonaventure.